Medical Weight Loss in Knoxville & Sevierville, TN

The pursuit of weight loss and body sculpting has seen a significant rise in recent years, thanks to advancements in both medical weight loss therapies and plastic surgery. One of the most promising breakthroughs in weight management is the use of GLP-1 receptor agonists, such as semaglutide (Ozempic®, Wegovy®), and GLP-1/GIP receptor agonists like tirzepatide (Mounjaro®).

A woman holding a scale and smiling after seeing results from medical weight loss in Knoxville

While these non-surgical treatments are highly effective for reducing body weight, they may leave behind excess skin or areas of stubborn fat, which is where body contouring procedures come in.

Dr. Dean Kleto, a board-certified and fellowship-trained plastic surgeon, offers medical weight loss and body contouring surgery. He guides patients through all stages of their health and aesthetic transformations, offering them the best of both worlds – noticeable weight loss and a sculpted, toned appearance.

Understanding Weight Loss Medications

Semaglutide is a GLP-1 receptor agonist. It was originally designed to treat type 2 diabetes but has gained widespread use for weight loss. These drugs work by mimicking the hormone glucagon-like peptide-1 (GLP-1), which regulates appetite, slows gastric emptying, and promotes insulin secretion. The result is reduced hunger and increased satiety, leading to considerable weight loss over time.

Tirzepatide combines GLP-1 and GIP receptor agonists. It works through dual action by targeting GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, which helps control appetite, improve insulin response, and support greater weight loss. In some cases, this dual mechanism can yield more noticeable and sustained results than GLP-1 medications alone.

Many patients experience a substantial decrease in body weight with these medications. Still, the rate and extent of weight loss can lead to aesthetic concerns such as loose skin, deflated fat pockets, and uneven body contours. While exercise and muscle strengthening can help, plastic surgery offers definitive solutions for reshaping the body after substantial weight loss.

Best Timing for Surgery

A woman holding her jeans away from her waist after GLP-1 weight loss injections in Sevierville

Plastic surgeons typically recommend waiting until the patient has maintained a stable weight for at least six months to achieve the best results. This ensures that the body is no longer undergoing drastic fluctuations, which can impact the longevity of surgical results. Additionally, patients should be in good overall health, have realistic expectations, and commit to a healthy lifestyle post-surgery.

Combining Non-Surgical Treatments

In addition to surgical procedures, non-surgical treatments like radiofrequency skin tightening, ultrasound therapy, and injectable fillers can enhance results. These options are particularly beneficial for patients with mild to moderate skin laxity who may not need surgery but want to improve their contours.

Why Choose Dr. Kleto?

Patients seeking medical weight loss treatments can trust Dr. Dean Kleto for his advanced training, surgical precision, and patient-centered approach.

Certified by the American Board of Plastic Surgery, Dr. Kleto brings decades of experience and refined techniques to each case. He also completed residencies at Duke University Medical Center and the University of Louisville, with specialized training in microsurgery.

Dr. Kleto’s personalized care and attention to detail help patients reach their goals and feel their best. With a compassionate chairside manner and a commitment to excellence, Dr. Kleto supports each patient through every step of their aesthetic and weight loss processes.

FAQs

Weight loss results with GLP-1 medications vary by individual. However, clinical studies show that patients can lose anywhere from 10% to 20% of their starting body weight over several months. Semaglutide and tirzepatide are particularly effective when they’re combined with a healthy diet and regular physical activity.

Results depend on consistency, lifestyle habits, and dosage. It’s also important to remember that these medications support gradual, sustainable weight loss, and outcomes may take time. Regular follow-ups with Dr. Kleto ensure the treatment plan stays on track and is adjusted as needed for the best results.

GLP-1 medications are generally well-tolerated. However, they can cause certain side effects, especially when starting treatment.

Common side effects include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Decreased appetite

These symptoms often lessen over time. A thorough consultation with Dr. Kleto will determine eligibility. He will also monitor for adverse effects during treatment to ensure it’s safe and effective for long-term use.

Maintaining weight loss and body contouring results requires a long-term commitment to healthy habits, including:

  • Eating a whole foods-based diet
  • Monitoring portion sizes
  • Exercising regularly
  • Staying hydrated
  • Attending routine follow-ups for ongoing support and adjustments

If you discontinue medical weight loss treatment, lifestyle habits are even more important to prevent rebound weight gain. Combining nutritional support, exercise, and mindful behaviors offers the best chance of keeping your results consistent and your health in check.

Schedule a Consultation Today

Combining GLP-1 weight loss medications and body contouring surgery presents a powerful approach to achieving significant weight loss and an aesthetically pleasing body shape. While GLP-1 medications help reduce excess weight, plastic surgery provides the finishing touches by addressing loose skin and refining body contours.

Patients considering this combination should consult a medical weight loss specialist and a board-certified plastic surgeon to create a personalized plan for their transformation. With the right approach, achieving a sculpted, healthy body is more attainable than ever.

Call Dr. Kleto’s office today at 865.524.2442 to schedule a consultation. He has locations in Knoxville and Sevierville, TN.

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